Systematic Literature Review: Phytochemistry and Antimalarial Activity of Carrica Papaya Linn

Diana Merna; Maipha Deapati Arief; Maria N. Keruru; Nicolaus Noywuli; Inggrid Kase; Daniel Simo

doi:10.53863/kst.v7i02.1653

Authors

Diana Merna Sekolah Tinggi Pertanian Flores, Bajawa, Indonesia
Maipha Deapati Arief Akademi Komunitas Industri Manufaktur Bantaeng, Indonesia
Maria N. Keruru Sekolah Tinggi Pertanian Flores, Bajawa, Indonesia
Nicolaus Noywuli Sekolah Tinggi Pertanian Flores, Bajawa, Indonesia
Inggrid Kase Sekolah Tinggi Pertanian Flores, Bajawa, Indonesia
Daniel Simo Sekolah Tinggi Pertanian Flores, Bajawa, Indonesia

DOI:

https://doi.org/10.53863/kst.v7i02.1653

Keywords:

Antimalarial activity, Carica papaya L, Phytochemical, Plasmodium falciparum

Abstract

Papaya leaves (Carica papaya L.) have been trusted and proven to antimalarial activity. Currently review information on morphology, phytochemical and pharmacology aspects of the papaya plant (Carica papaya L). Based on a literature study on papaya plants (Carica papaya L.) summarized from ScienceDirect, Google Scholar, Springer with search keys morphology, phytochemical, antimalarial, Carica papaya L, plasmodium falciparum, papaya leaf extract has antimalarial activity against plasmodium falciparum. Qualitative phytochemical analysis of papaya leaf extract (Carica papaya L) showed the presence of alkaloids, flavonoids, saponins, tannins, and glycosides. Flavonoids showed antimalarial activity against P. falcifarum which inhibited the entry of L-glutamine and myoinositol into infected erythrocytes during the intraerthrocytic phase of the Plasmodium life cycle.

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