Analisis Deskriptif dengan Kombinasi AI (Artificial Intelligence) Tentang Penggunaan Obat pada Pasien Penyakit Degeneratif di Puskesmas Tirtajaya Tahun 2025

Authors

  • Dwi Wulan Apriani Politeknik Kesehatan Borneo Citra Medika, Kalimantan Selatan, Indonesia
  • Tio Widia Astuti Marpaung Politeknik Kesehatan Borneo Citra Medika, Kalimantan Selatan, Indonesia
  • Adelina Sisilia Politeknik Kesehatan Borneo Citra Medika, Kalimantan Selatan, Indonesia
  • Lenny Andika Politeknik Kesehatan Borneo Citra Medika, Kalimantan Selatan, Indonesia
  • Ayin Ayin Politeknik Kesehatan Borneo Citra Medika, Kalimantan Selatan, Indonesia

DOI:

https://doi.org/10.53863/kst.v8i02.2459

Keywords:

drug combination; artificial intelligence; drug-related problems; primary health center; medication rationality

Abstract

Degenerative diseases such as hypertension, type 2 diabetes mellitus (DM), stroke, and osteoarthritis are non-communicable diseases whose prevalence continues to rise along with increasing life expectancy and lifestyle changes, and these conditions frequently occur in combination within the same patient. Appropriate drug use is an important indicator of pharmaceutical service quality at primary health care facilities. This study aimed to analyze the pattern of drug use and evaluate its rationality among patients with combined degenerative diseases at Tirtajaya Public Health Center throughout 2025, incorporating artificial intelligence (AI) as a supporting tool for descriptive analysis, data categorization, and literature synthesis. This was a descriptive observational study with retrospective data collection using secondary data on visits, diagnoses, treatments, and laboratory results from 1 January to 31 December 2025. Of 408 patients diagnosed with degenerative disease, 102 patients met the inclusion criteria. Type 2 DM was the most common condition (51.0%), followed by osteoarthritis (31.4%), hypertension (15.7%), and stroke (7.8%). Most patients were female (68.6%) and aged 45-54 years (34.3%), with 90.2% having comorbidities, mainly secondary hypertension and dyslipidemia. Rationality evaluation of 291 prescription items for degenerative disease therapy showed 56.7% correct indication, 91.4% correct drug selection, 90.0% correct patient, and 93.5% correct dosage. Indication inaccuracies were mostly attributable to incomplete recording of comorbid diagnoses, while the use of oral corticosteroids for chronic osteoarthritis was identified as a deviation from Pionas standards. This study concludes that drug use among patients with combined degenerative diseases at Tirtajaya Public Health Center is generally rational, although completeness of diagnosis documentation and monitoring of high-risk groups still need improvement, and AI-assisted approaches may support the efficiency of similar descriptive analyses in the future

References

Anggriani, A., Lisni, I., & Faujiah, D. S. R. (2016). Analisis masalah terkait penggunaan obat pada pasien lanjut usia penderita osteoartritis di Poli Ortopedi salah satu rumah sakit di Bandung. Kartika Jurnal Ilmiah Farmasi, 4(2), 13–20. https://doi.org/10.26874/kjif.v4i2.61

Badan Pengawas Obat dan Makanan Republik Indonesia. (t.t.). Pusat Informasi Obat Nasional (Pionas). Diakses dari https://pionas.pom.go.id

Bijlsma, J. W. J., Berenbaum, F., & Lafeber, F. P. J. G. (2011). Osteoarthritis: An update with relevance for clinical practice. The Lancet, 377(9783), 2115–2126. https://doi.org/10.1016/S0140-6736(11)60243-2

Bringhurst, K., Jones, T., Runko, G., Jabbari, M., Zipparro, N., Vo, G. N., Ullah, A., Vo, T. M., Corrigan, M., Birrey, V., & Jacobs, R. J. (2025). Artificial intelligence in the management of polypharmacy among older adults: A scoping review. Cureus, 17(8), e90867. https://doi.org/10.7759/cureus.90867

Cabello, J. B., Ruiz Garcia, V., Torralba, M., Maldonado Fernandez, M., Ubeda, M., Ansuategui, E., Ramos-Ruperto, L., Emparanza, J. I., Urreta, I., Iglesias, M. T., Pijoan, J. I., & Burls, A. (2025). Critical appraisal tools for evaluating artificial intelligence in clinical studies: Scoping review. Journal of Medical Internet Research, 27, e77110. https://doi.org/10.2196/77110

Char, D. S., Shah, N. H., & Magnus, D. (2018). Implementing machine learning in health care — Addressing ethical challenges. New England Journal of Medicine, 378(11), 981–983. https://doi.org/10.1056/NEJMp1714229

Davenport, T., & Kalakota, R. (2019). The potential for artificial intelligence in healthcare. Future Healthcare Journal, 6(2), 94–98. https://doi.org/10.7861/futurehosp.6-2-94

Ismail, S., Stanley, A., & Jeemon, P. (2022). Prevalence of multimorbidity and associated treatment burden in primary care settings in Kerala: A cross-sectional study in Malappuram District, Kerala, India. Wellcome Open Research, 7, 67. https://doi.org/10.12688/wellcomeopenres.17674.2

James, P. A., Oparil, S., Carter, B. L., Cushman, W. C., Dennison-Himmelfarb, C., Handler, J., Lackland, D. T., LeFevre, M. L., MacKenzie, T. D., Ogedegbe, O., Smith, S. C., Svetkey, L. P., Taler, S. J., Townsend, R. R., Wright, J. T., Narva, A. S., & Ortiz, E. (2014). 2014 evidence-based guideline for the management of high blood pressure in adults: Report from the panel members appointed to the Eighth Joint National Committee (JNC 8). JAMA, 311(5), 507–520.

Katonai, G., Arvai, N., & Mesko, B. (2025). AI and primary care: Scoping review. Journal of Medical Internet Research, 27, e65950. https://doi.org/10.2196/65950

Kementerian Kesehatan Republik Indonesia. (t.t.). Formularium Nasional. Jakarta: Kementerian Kesehatan RI.

Li, Y., Geng, S., Yuan, H., Ge, J., Li, Q., Chen, X., Zhu, Y., Liu, Y., Guo, X., Wang, X., & Jiang, H. (2024). Multimorbidity in elderly patients with or without T2DM: A real-world cross-sectional analysis based on primary care and hospitalisation data. Journal of Global Health, 14, 04263. https://doi.org/10.7189/jogh.14.04263

Martínez-Martínez, H., Martínez-Alfonso, J., Sánchez-Rojo-Huertas, B., Reynolds-Cortez, V., Turégano-Chumillas, A., Meseguer-Ruiz, V. A., Cekrezi, S., & Martínez-Vizcaíno, V. (2025). Perceptions of, barriers to, and facilitators of the use of AI in primary care: Systematic review of qualitative studies. Journal of Medical Internet Research, 27, e71186. https://doi.org/10.2196/71186

Olender, R. T., Roy, S., & Nishtala, P. S. (2025). Potentially inappropriate polypharmacy is an important predictor of 30-day emergency hospitalisation in older adults: A machine learning feature validation study. Age and Ageing, 54(6), afaf156. https://doi.org/10.1093/ageing/afaf156

Perhimpunan Dokter Hipertensi Indonesia (INASH). (t.t.). Konsensus penatalaksanaan hipertensi. Jakarta: INASH.

Perkumpulan Endokrinologi Indonesia (PERKENI). (2021). Pedoman pengelolaan dan pencegahan diabetes melitus tipe 2 dewasa di Indonesia. Jakarta: PB PERKENI.

Rajkomar, A., Dean, J., & Kohane, I. (2019). Machine learning in medicine. New England Journal of Medicine, 380(14), 1347–1358. https://doi.org/10.1056/NEJMra1814259

Ramdini, D. A., Wahidah, L. K., & Atika, D. (2020). Evaluasi rasionalitas penggunaan obat diabetes melitus tipe II pada pasien rawat jalan di Puskesmas Pasir Sakti tahun 2019. Jurnal Farmasi Lampung, 9(1), 69–76. https://doi.org/10.37090/jfl.v9i1.334

Sasseville, M., Ouellet, S., Rhéaume, C., Sahlia, M., Couture, V., Després, P., Paquette, J.-S., Darmon, D., Bergeron, F., & Gagnon, M.-P. (2025). Bias mitigation in primary health care artificial intelligence models: Scoping review. Journal of Medical Internet Research, 27, e60269.

Topol, E. J. (2019). High-performance medicine: The convergence of human and artificial intelligence. Nature Medicine, 25(1), 44–56. https://doi.org/10.1038/s41591-018-0300-7

Wulandari, A., & Ardhianingsih, V. (2021). Evaluasi pemberian dan penggunaan obat antihipertensi pada pasien lansia di Puskesmas Sukarami Palembang. INPHARNMED Journal (Indonesian Pharmacy and Natural Medicine Journal), 5(2), 1–7.

Published

2026-08-13

How to Cite

Apriani, D. W., Marpaung, T. W. A., Sisilia, A., Andika, L., & Ayin, A. (2026). Analisis Deskriptif dengan Kombinasi AI (Artificial Intelligence) Tentang Penggunaan Obat pada Pasien Penyakit Degeneratif di Puskesmas Tirtajaya Tahun 2025. Jurnal Kridatama Sains Dan Teknologi, 8(02), 584–596. https://doi.org/10.53863/kst.v8i02.2459

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